#Co-first authors
*corresponding author(s)
2022
49. Petrovic, S., Samanta, D. , Perriches, T., Bley, C.J., Thierbach, K., Brown, B., Nie, S., Mobbs ,G.W., Stevens, T.A., Liu, X., Tomaleri, G.P., Schaus, L., Hoelz A., Architecture of the linker-scaffold in the nuclear pore. (2022) Science 376: eabm9798, doi:10.1126/science.abm9798
48. Bley, C.J., Nie, S., Mobbs, G.W., Petrovic, S., Gres, A.T., Liu, X., Mukherjee, S., Harvey, S., Huber, F.M., Lin, D.H., Brown, B., Tang, A.W., Rundlet, E.J., Correia, A.R., Chen, S., Regmi, S.G., Stevens, T.A., Jette, C.A., Patke, A., Dasso, M., Palazzo, A.F., Kossiakoff, A.A., Hoelz, A. (2022). Architecture of the cytoplasmic face of the nuclear pore. Science, 376, eabm9129, doi:10.1126/science.abm9798
47. Petrovic S., Hoelz, A. (2022). Forced entry into the nucleus. Nat. Cell Bio. https://doi.org/10.1038/s41556-022-00939-3
2020
46. Mobbs, G.W., Hoelz, A. (2020). Nucleoporin Condensates Drive Nuclear Pore Complex Assembly in Oocytes. Trends Biochem Sci. 45 (4), 278-280
2019
45. Lin, D.H., Hoelz, A. (2019). The Structure of the Nuclear Pore Complex (An Update). Annu. Rev. Biochem. 88, 725-783 (https://doi.org/10.1146/annurev-biochem-062917-011901)
2018
44. Skubák, P., Araç, D., Bowler, M.W., Correia, A.R., Hoelz, A., Larsen, S., Leonard, G.A., McCarthy, A.A., McSweeney, S., Mueller-Dieckmann, C., Otten, H., Salzman, G., Pannu, N.S. (2018). A new MR-SAD algorithm for the automatic building of protein models from low-resolution X-ray data and a poor starting model. IUCrJ., 5, 166-171
43. Lin, D. H., Correia, A.C., Cai, S.W., Huber, F.M. Jette, C.A., Hoelz, A. (2018). Structural and functional analysis of mRNA export regulation by the nuclear pore complex. Nat. Commun., 2319
42. Hoelz, A. (2018). Günter Blobel (1936-2018). Nat. Cell Biol., 20, 364
2017
41. Huber, F.M., # Greenblatt, S.M., # Davenport, A.M., # Martinez, C., Xu, Y., Vu, L.P., Nimer, S.D.,* Hoelz, A.* (2017). Histone-binding of DPF2 mediates its repressive role in myloid differentiation. Proc. Natl. Acad. Sci. USA, 114, 6016-6021.
40. Huber, F.M. and Hoelz, A. (2017). Molecular basis for protection of ribosomal protein L4 from cellular degradation. Nat. Commun., 14354
2016
39. Lin, D.H., Hoelz, A. (2016). Nuclear Comings and Goings. The Scientist, 12.2016 (24-29)
38. Sung, M.K., Porras-Yakushi, T.P., Reitsma, J.M., Huber, F.M., Sweredoski, M.J., Hoelz, A., Hess, S., Deshaies, R.* (2016). A conserved quality-control pathway that mediates degradation of unassembled ribosomal proteins. eLife, 5, e19105
37. Hoelz, A.*, Glavey, J.,* Beck, M.* (2016). Toward the atomic structure of the nuclear pore complex: when top down meets bottom up. NSMB, 23, 624-630.
36. Lin, D.H., # Stuwe, T.,# Schilbach, S., Rundlet, E.R., Perriches, T., Mobbs, G., Fan, Y., Thierbach, K., Huber, F.M., Collins, L.N, Davenport, A.M., Jeon, Y.J., Hoelz, A.* (2016). Architecture of the symmetric core of the nuclear pore. Science, 352, 308.
2015
35. Stuwe, T.T.,# Bley, C.J. ,# Thierbach, K., # Petrovic, S., # Schilbach, S., Mayo, D.J., Perriches, T., Rundlet, E.J., Jeon, Y.J., Collins, L.N., Huber, F.M., Lin, D.H., Paduch, M., Koide, A., Lu, V., Fischer, J., Hurt, E., Koide, S., Kossiakoff, A., Hoelz, A.* (2015). Architecture of the fungal nuclear pore inner ring complex. Science, 350, 56-64.
34. Stelter, P.,# Huber, F.M.,# Kunze, R., Flemming, D., Hoelz, A.*, Hurt, E.* (2015). Coordinated Ribosomal L4 Protein Assembly into the Pre-Ribosome Is Regulated by Its Eukaryote-Specific Extension. Mol. Cell, 58, 854-862.
* Featured on the cover
33. Stuwe, T.T.,# Correia, A.R.,# Lin, D.H., Paduch, M., Lu, V.T., Kossiakoff, A., Hoelz, A.* (2015). Architecture of the nuclear pore complex coat. Science, 347, 1148-1152.
2014
32. Davenport, A.M., Collins, L.N., Chiu, H., Minor, P.J., Sternberg, P.W., Hoelz, A.* (2014). Structural and Functional Characterization of the α-tubulin acetyltransferase MEC-17. J. Mol. Biol. 426, 2605-2616.
31. Stuwe, T.T.,# Lin, D.H.,# Collins, L.N., Hurt, E., Hoelz, A.* (2014). Evidence for an evolutionary relationship between the large adaptor nucleoporin Nup192 and karyopherins. Proc. Natl. Acad. Sci. USA 111, 2530-2535.
30. Davenport, A.M., Huber, F.M., Hoelz, A.* (2014). Structural and Functional Analysis of Human SIRT1. J. Mol. Biol. 426, 526-541.
* Featured on the cover
2013
29. Lin, D.H., Zimmermann, S., Stuwe, T.S., Stuwe, E., Hoelz, A.* (2013). Structural and Functional Analysis of the C-terminal Domain of Nup358/RanBP2. J. Mol. Biol. 425, 1318-1329.
* Featured on the cover
2012
28. Kassube, S.A., Stuwe, T.S., Lin, D.H., Antonuk, C.D., Napetschnig, J., Blobel, G., Hoelz, A.* (2012). Crystal structure of the N-terminal domain of Nup358/RanBP2. J. Mol. Biol. 423, 752-765.
27. Stuwe, T.S., Schada von Borzyskowski, L., Davenport, A.M., Hoelz, A. (2012). Molecular Basis for the Anchoring of Proto-Oncoprotein Nup98 to the Cytoplasmic Face of the Nuclear Pore Complex. J. Mol. Biol. 419, 330-346.
* Featured on the cover
2011
26. Yoshida, K., Seo, H.S., Debler, E.W., Blobel, G., Hoelz, A. (2011). Structural and functional analysis of an essential heterotrimer on the cytoplasmic face of the nuclear pore complex. Proc. Natl. Acad. Sci. USA 108, 16571-16576.
25. King, H.A., Hoelz, A., Crane, B.R., Young, M.W. (2011). Structure of an enclosed dimer formed by the drosophila period protein. J. Mol. Biol. 413, 561-572.
24. Stuwe, T.S., Hoelz, A. (2011). Rae1: A new clue for nucleoporin leukemias. Cell Cycle 10, 2056.
23. Hoelz, A.*,**, Debler, E.W., Blobel, G. (2011). Structure of the Nuclear Pore Complex. Annu. Rev. Biochem. 80, 613-643.
** invited author
2010
22. Hsia, K.C., Hoelz, A. (2010). Crystal structure of α-COP in complex with ε-COP provides insight into the architecture of the COPI vesicular coat. Proc. Natl. Acad. Sci. USA 107, 11271-11276.
** Highlighted in Nature
21. Ren, Y., Seo, H.S., Blobel, G., Hoelz, A. (2010). Structural and functional analysis of the interaction between the nucleoporin Nup98 and the mRNA export factor Rae1. Proc. Natl. Acad. Sci. USA 107, 10406-10411.
20. Debler, E.W., Hsia, K.C., Nagy, V., Seo, H.S., Hoelz, A. (2010). Characterization of the membrane-coating Nup84 complex: Paradigm for the nuclear pore complex structure. Nucleus 1, 150-156.
2009
19. Nagy, V., Hsia, K.C., Debler, E.W., Kampmann, M., Davenport, A.M., Blobel, G., Hoelz, A. (2009). Structure of a trimeric nucleoporin complex reveals alternate oligomerization states. Proc. Natl. Acad. Sci. USA 106, 17693-17698.
18. Seo, H.S., Ma, Y., Debler, E.W., Wacker, D., Kutik, S., Blobel, G., Hoelz, A. (2009). Structural and functional analysis of Nup120 suggests ring formation of the Nup84 complex. Proc. Natl. Acad. Sci. USA 106, 14281-14286.
17. Debler, E.W., Blobel, G., Hoelz, A. (2009). Nuclear transport comes full circle. Nat. Struct. Mol. Biol. 16, 457-459.
16. Napetschnig, J., Kassube, S.A., Debler, E.W., Wong, R.W., Blobel, G. and Hoelz, A. (2009). Structural and functional analysis of the interaction between the nucleoporin Nup214 and the DEAD-box helicase Ddx19. Proc. Natl. Acad. Sci. USA 106, 3089-3094.
2008
15. Debler, E.W., Ma, Y., Seo, H.S., Hsia, K.C., Noriega, T.R., Blobel, G., Hoelz, A. (2008). A fence-like coat for the nuclear pore membrane. Mol. Cell 32, 815-826.
* Featured on the cover
14. Stavropoulos, P., Nagy, V., Blobel G., Hoelz A. (2008). Molecular basis for the autoregulation of the protein acetyl transferase Rtt109. Proc. Natl. Acad. Sci. USA 105, 12236-12241.
2007
13. Hsia, K.C., Stavropoulos, P., Blobel, G., Hoelz, A. (2007). Architecture of a coat for the nuclear pore membrane. Cell 131, 1313-1326.
12. Stavropoulos, P. and Hoelz, A. (2007). Lysine-specific demethylase 1 as a potential therapeutic target. Expert Opin. Ther. Targets 11, 809-920.
11. Melcak, I., Hoelz, A.*, Blobel, G.* (2007). Structure of Nup58/45 suggests flexible nuclear pore diameter by intermolecular sliding. Science 315, 1729-1732.
** Highlighted in Cell and the Journal of Cell Biology
10. Napetschnig, J., Blobel, G., Hoelz, A. (2007). Crystal structure of the N-terminal domain of the human protooncogene Nup214/CAN. Proc. Natl. Acad. Sci. USA 104, 1783-1788.
2006
9. Pirruccello, M., Sondermann, H., Pelton, J.G., Pellicena, P., Hoelz, A., Chernoff, J., Wemmer, D.E., Kuriyan, J. (2006). A dimeric kinase assembly underlying autophosphorylation in the p21 activated kinases. J. Mol. Biol. 361, 312-326.
8. Stavropoulos, P., Blobel, G., Hoelz, A. (2006). Crystal structure and mechanism of human lysine-specific demethylase-1. Nat. Struct. Mol. Biol. 13, 626-632.
* Faculty of 1000: must read
7. Hoelz, A.*, Janz, J.M., Lawrie, S.D., Corwin, B., Lee, A., Sakmar, T.P.* (2006). Crystal structure of the SH3 domain of βPIX in complex with a high affinity peptide from PAK2. J. Mol. Biol. 358, 509-522.
6. Rosenberg, O.S., Deindl, S., Comolli, L.R., Hoelz, A., Downing, K.H., Nairn, A.C., Kuriyan, J. (2006). Oligomerization states of the association domain and the holoenyzme of Ca2+/CaM kinase II. FEBS J. 273, 682-694.
** Featured on the cover
2004
5. Hoelz, A.*, Blobel, G.* (2004). Cell biology: popping out of the nucleus. Nature 432, 815-816.
2003
4. Hoelz, A., Nairn, A. C., Kuriyan, J. (2003). Crystal structure of a tetradecameric assembly of the association domain of Ca2+/calmodulin-dependent kinase II. Mol. Cell 11, 1241-1251.
** Featured on the Cover, highlighted in Nature Reviews Molecular Cell Biology
3. Margarit, S. M., Sondermann, H., Hall, B. E., Nagar, B., Hoelz, A., Pirruccello, M., Bar-Sagi, D., Kuriyan, J. (2003). Structural evidence for feedback activation by Ras•GTP of the Ras-specific nucleotide exchange factor SOS. Cell 112, 685-695.*
* Faculty of 1000: must read
1999
2. Schenk, S., Hoelz, A., Decker, K. (1999) A novel heterotrimeric flavoprotein involved in bacterial nicotine degradation. In Flavins and Flavoproteins, Ghisla, S., Kroneck, P., Macheroux, P., Sund, H., eds., (Rudolf Weber, Berlin. Agency for Scientific Publications), pp. 427–430.
1. Schenk, S., Hoelz, A., Krauß, B., Decker, K. (1998). Gene structures and properties of enzymes of the plasmid -encoded nicotine catabolism of Arthrobacter nicotinovorans. J. Mol. Biol. 284, 1323-1339.
